Dental
NovioBone DBM Putty, Cancellous Cubes, Soft Tissue Membranes
Regenerative solutions for dental procedures require precision, biological compatibility, and predictable healing. NovioTissue’s dental portfolio is designed to support bone and soft tissue regeneration across a wide range of clinical scenarios, from implant site development to defect repair. By combining human-derived graft materials with easy-to-handle formats, these solutions promote cellular integration, vascularization, and long-term stability—helping clinicians achieve reliable outcomes in both routine and complex dental procedures.
Designed to Restore Structure, Stability, and Confidence in Dental Regeneration
NovioBone DBM Putty
Noviotissue introduces a next-generation solution for dental bone void filling with the NovioBone DBM Putty portfolio. Developed specifically to support dental regenerative procedures, this portfolio offers clinicians and partners three distinct formulations designed for excellent handling, adaptability, and regenerative performance. Manufactured in Europe and supported by proven clinical utility, NovioBone DBM Putty delivers a reliable, ready-to-use solution tailored to the demands of modern dental surgery.
Key Benefits:
- Biologically derived components.
- Moldable, easy-to-handle putty consistency.
- Sterile, single-use packaging.
- Versatile across a wide range of dental regenerative procedures.
4 Formulations To Fit Any Need
Not all DBM putties deliver the same results. NovioBone DBM Putty is designed specifically for dental regeneration, offering formulations tailored to the precision and handling requirements of modern dental procedures. At Noviotissue, we’ve created four distinct DBM formulations to support predictable outcomes across diverse dental applications.
Injectable
100% human DBM with a medium viscosity biobased carrier for smooth delivery.
Injectable +
100% human DBM with human derived carrier; a 100% human product.
Injectable Crunch
DBM with cancellous chips for added structure with a medium viscosity biobased carrier.
Paste
100% human DBM with a higher viscosity biobased carrier for better graft retention.
Local Manufacturing and Distribution
There are limited sources of DBM putty manufactured within Europe, and at NovioTissue, we view this as an opportunity to support dental clinicians with locally available, high-quality regenerative solutions. By producing DBM putty in the EU, we provide versatile formats tailored to the precision and predictability required in dental procedures. NovioTissue is the EU’s newest trusted source for DBM putty—manufactured in Europe and designed to support modern dental regeneration.
Why source graft materials from overseas when reliable, locally produced solutions are within reach?
Every syringe of NovioBone DBM Putty is created with dental practice in mind:
Processed within the European Union. Produced under rigorous quality and compliance standards. Reduced lead times for dependable availability. Trusted sourcing you can rely on. Responsive support for dental professionals.
Regulatory Excellence and Proven Orthopaedic Performance
At NovioTissue, we’ve redefined the DBM experience for dental procedures—delivering smoother handling, greater formulation flexibility, and consistent performance clinicians can rely on. From socket preservation to ridge augmentation, DBM continues to play a critical role in dental bone regeneration—and today, it’s more refined than ever.
Did You Know?
DBM was originally discovered to be osteoinductive by accident in the 1960s, when researchers noticed that demineralized bone implanted into animals triggered the unexpected formation of new bone in places bone shouldn’t normally grow. That surprise finding ended up becoming one of the foundations of modern biologics.
Why does DBM still matter?
Because it remains one of the most trusted materials in dental bone grafting—supported by real clinical outcomes and long-standing use.
- Osteoinductive and osteoconductive properties
- Derived from human tissue
- Supported by decades of clinical use in dental regeneration
Whether you’re performing a focused graft requiring minimal volume or managing a more complex augmentation, NovioBone DBM Putty offers multiple formulation and volume options to match procedural needs:
- Injectable — 0.5 cc, 1.0 cc, 2.5 cc, 5.0 cc, 10 cc.
- Injectable Plus — 0.5 cc, 1.0 cc, 2.5 cc, 5.0 cc, 10 cc.
- Injectable Crunch — 0.5 cc, 1.0 cc, 2.5 cc, 5.0 cc, 10 cc.
- Paste — 0.5 cc, 1.0 cc.
Download the Product Brochure for More Information!
NovioBone DBM Putty is a 100% human-derived demineralized bone matrix designed to meet the precision and handling demands of dental bone regeneration. The smooth, moldable putty adapts easily to confined and irregular defect sites, allowing controlled placement and stability during grafting procedures. With osteoconductive and osteoinductive properties inherent to DBM, NovioBone DBM Putty supports new bone formation without synthetic additives or carriers. Its ready-to-use format makes it an effective solution for dental applications where predictable integration and reliable defect fill are essential.
Cancellous Cubes
Engineered for both biological performance and clinical efficiency, these allograft-based materials provide a natural scaffold that supports osteoconduction and osteoinduction in dental and maxillofacial procedures. Their versatile handling properties make them ideal for use in socket preservation, ridge augmentation, sinus lifts, and periodontal regeneration, where traditional grafts may be difficult to shape or stabilize. By combining strength, flexibility, and biocompatibility, these advanced bone matrices help dental surgeons achieve stable graft placement and predictable osseointegration, even in anatomically challenging sites.
Key Benefits:
- Simplified Placement.
- Secure Defect Conformity.
- Enhanced Biological Integration.
- Predictable Remodeling.
Key Features:
- Compressible Sponge Format.
- Fluid-Activated Expansion.
- High-Porosity Matrix.
- Ready-to-Use Design.
- Cortico-Cancellous Graft Composition.
Clinical Applications:
- Socket preservation following tooth extraction.
- Ridge augmentation for implant placement.
- Sinus floor elevation procedures.
- Periodontal and peri-implant defect regeneration.
- Small to medium alveolar bone defects.
Indications For Use:
- Alveolar ridge deficiencies.
- Extraction socket grafting.
- Implant site preparation.
- Defect filling after cyst or tumor removal.
- Defect filling following debridement of periodontal or alveolar bone.
Product Handling
Cancellous Cubes can be applied directly to the dental defect site. Compress the cube slightly before placement; upon exposure to blood or saline, it expands to fill the space and conform to surrounding bone. Stable fixation is typically achieved without additional hardware, making the graft easy to adapt in both open and minimally invasive procedures.
Versatile Bone Graft for Dental Regeneration
Cancellous Cubes are designed to meet the demands of dental bone repair and regeneration. Each cube acts as a dynamic scaffold composed of cortico-cancellous grafts integrated with gelatin and hyaluronic acid. This combination provides excellent handling, adaptability, and biological performance for procedures such as ridge preservation, guided bone regeneration, and sinus augmentation.
The compressible structure allows surgeons to easily shape and position the graft into irregular alveolar defects. Upon contact with blood or other physiological fluids, the cubes expand—ensuring optimal defect fill, stable placement, and intimate contact with surrounding bone. The resulting increase in porosity facilitates cellular migration, angiogenesis, and new bone formation, supporting faster and more predictable healing.
Did You Know?
Cancellous cubes are so porous that they’re often compared to natural “biological sponges.” Surgeons love them because those tiny trabecular pathways act like highways for cells and blood vessels. A single cubic centimeter of cancellous bone can contain over 70 percent air space, which is one reason it integrates so well once it’s implanted.
Soft Tissue Membranes
Amnion
The need for a reliable, high-quality soft tissue repair solution in dentistry has never been greater. This next-generation regenerative membrane provides an effective, compliant option for oral soft tissue healing and protection in a variety of dental procedures. Designed for adaptability, the repair system conforms easily to different defect shapes and sizes, supporting predictable outcomes across periodontal, implant, and surgical applications.
Its simplified handling allows for chairside use in standard dental procedures, supporting efficient treatment without adding complexity to the clinical workflow.
Key Advantages:
Ultra-thin (<0.1 mm) design enables precise placement and natural integration with oral tissues. Bioactive properties support soft tissue healing while helping minimize inflammation and scarring. Ready-to-use format streamlines application and post-operative management
This amniotic-derived membrane is developed from human amniotic tissue, selected for its natural elasticity, strength, and protective properties that are well suited for oral soft tissue management. Sourced following cesarean deliveries, the tissue undergoes a proprietary decellularization process designed to preserve the native extracellular matrix (ECM), which plays a critical role in supporting tissue healing.
Manufactured in compliance with EU regulatory guidelines, the membrane functions as a bioactive protective barrier for dental applications, maintaining flexibility and structural integrity to support healing in periodontal, implant, and oral surgical procedures. The decellularization process utilizes supercritical CO₂ technology, preserving the membrane’s natural architecture while optimizing its regenerative performance.
With a thickness of less than 0.1 mm, the membrane serves as a conformable, bioactive wound dressing that adheres upon contact with moist oral tissues. Its ultra-thin profile simplifies placement, supports efficient postoperative management, and is valued for its ease of handling, storage, and chairside use in dental practices.
Regulatory Excellence and Clinical Versatility
This amniotic-derived membrane adheres to European regulatory standards, ensuring safety and effectiveness as a biologic graft for dental applications. Manufactured using supercritical CO₂ decellularization technology, it preserves the structural integrity, elasticity, and strength of the amniotic membrane, supporting consistent regenerative performance in the oral environment.
Well suited for revision and challenging dental cases, the membrane offers a minimally invasive solution for sites with compromised healing or previous surgical intervention, including periodontal, implant, and oral surgery procedures. Constructed from amnion extracellular matrix, clinical evidence demonstrates its ability to support natural healing processes while providing high tensile strength, durability, and flexibility.
The membrane’s inherent adhesive properties ensure secure coverage over surgical sites, while its function as a protective barrier supports optimal wound healing. With no preparation required, it simplifies chairside application, making it a convenient and effective option for both clinicians and patients in dental treatment settings.
“Flexibly adapts to different defect shapes and sizes for seamless oral tissue integration.”
Dermis
Not every oral soft tissue defect requires invasive surgical intervention. This regenerative patch provides an innovative solution for patients who need an effective, tissue-supportive approach to healing in dental procedures. It is engineered to eliminate the need for a secondary donor site, helping clinicians achieve optimal outcomes while minimizing patient morbidity.
With these advantages, the system represents a meaningful advancement in dental soft tissue management, offering a safer, more predictable healing experience across periodontal, implant, and oral surgery applications.
Key Benefits:
✅ Customizable to various defect sizes and shapes, supporting minimally invasive dental procedures
✅ Supports natural tissue regeneration, promoting safe and effective oral soft tissue healing
✅ Provides structural support for more complex regenerative needs in periodontal and implant-related procedures
“A Safe, Reliable Alternative to Autologous Tissue Harvesting”
Regulatory Excellence and Clinical Versatility
Dermis meets European regulatory standards, ensuring safety and reliability for dental soft tissue applications. Designed as a bioactive graft, Dermis supports natural oral tissue healing while helping minimize patient morbidity. Key clinical benefits include:
- Suturable Design: Its specialized composition allows for direct suturing, enabling precise placement and secure fixation during periodontal, implant, and oral surgical procedures.
- Proven Clinical Performance: Dermis has demonstrated consistent clinical outcomes, supporting its reliability and effectiveness in dental patient care.
- Reduced Patient Morbidity: By eliminating the need for a secondary donor site, Dermis helps reduce the risk of infection, scarring, and postoperative discomfort, contributing to a smoother recovery process.
- Enhanced Mechanical Strength: Engineered for durability, Dermis offers superior mechanical resistance to support effective soft tissue healing in the oral environment.
CaseStudies
Oral soft tissue defects in dentistry—such as gingival recession, surgical wounds after implant placement, and periodontal defects—vary widely in size and etiology. While conventional connective tissue grafts and barrier membranes remain standards of care, biologic membranes derived from amniotic tissue have been studied for their regenerative and wound-healing properties in dental settings. These membranes can serve as bioactive barriers or dressings that support natural tissue regeneration, improve epithelialization, reduce postoperative discomfort, and simplify clinical procedures without the need for a secondary donor site. The following studies illustrate their application and outcomes in dental tissue healing and regeneration.
Gurinsky, B.S.
A novel dehydrated amnion allograft for use in the treatment of gingival recession: an observational case series.
Journal of Implant and Advanced Clinical Dentistry. 2009; 1(1):65–73
https://pubmed.ncbi.nlm.nih.gov/31819667/
Kesting, M.R., et al.
Cryopreserved amniotic membrane for soft tissue healing after dental implant surgery: a randomized controlled clinical trial.
Clinical Oral Implants Research. 2010; 21(10):1019–1025
https://pubmed.ncbi.nlm.nih.gov/20629549/
Chopra, A., et al.
Comparative evaluation of amniotic membrane and collagen membrane in the treatment of gingival recession using guided tissue regeneration: a clinical study.
Journal of Periodontology. 2019; 90(9):991–1000
https://pubmed.ncbi.nlm.nih.gov/30631230/
Order Information
Use the following information when filling out your purchase order. To obtain individual/box-quantity pricing, or to submit a purchase order, contact your local distributor. To find a local distributor, submit a contact form on our contact us page.
Code | Description | Diameter / Dimensions / Volume | Thickness |
NT1005FD | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 0.5 CC | Medium Viscosity |
NT1020FD | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 1.0 CC | Medium Viscosity |
NT1025FD | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 2.5 CC | Medium Viscosity |
NT1050FD | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 5.0 CC | Medium Viscosity |
NT1060FD | NovioBone DBM Putty Injectable; 100% DBM with Biobased Carrier | 10.0 CC | Medium Viscosity |
NT1505FD | NovioBone DBM Putty Injectable Plus; 100% DBM with Human Carrier | 0.5 CC | Medium Viscosity |
NT1510FD | NovioBone DBM Putty Injectable Plus; 100% DBM with Human Carrier | 1.0 CC | Medium Viscosity |
NT1525FD | NovioBone DBM Putty Injectable Plus; 100% DBM with Human Carrier | 2.5 CC | Medium Viscosity |
NT1550FD | NovioBone DBM Putty Injectable Plus; 100% DBM with Human Carrier | 5.0 CC | Medium Viscosity |
NT1560FD | NovioBone DBM Putty Injectable Plus; 100% DBM with Human Carrier | 10.0 CC | Medium Viscosity |
NT1105FD | NovioBone DBM Putty Injectable Crunch; 100% DBM and Cancellous with Biobased Carrier | 0.5 CC | Medium Viscosity |
NT1110FD | NovioBone DBM Putty Injectable Crunch; 100% DBM and Cancellous with Biobased Carrier | 1.0 CC | Medium Viscosity |
NT1125FD | NovioBone DBM Putty Injectable Crunch; 100% DBM and Cancellous with Biobased Carrier | 2.5 CC | NT1110FD |
NT1150FD | NovioBone DBM Putty Injectable Crunch; 100% DBM and Cancellous with Biobased Carrier | 5.0 CC | NT1110FD |
NT1160FD | NovioBone DBM Putty Injectable Crunch; 100% DBM and Cancellous with Biobased Carrier | 10.0 CC | NT1110FD |
NT1205FD | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 0.5 CC | High Viscosity |
NT1210FD | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 1.0 CC | High Viscosity |
NT1220FD | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 2.0 CC | High Viscosity |
NT1225FD | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 2.5 CC | High Viscosity |
NT1250FD | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 5.0 CC | High Viscosity |
NT1260FD | NovioBone DBM Putty Paste; 100% DBM with Biobased Carrier | 10.0 CC | High Viscosity |
NT0040FD | NovioBone Cancellous Cubes | 10 x 10 MM | 10 MM |
NT0041FD | NovioBone Cancellous Cubes | 10 x 10 MM | 20 MM |
NT0042FD | NovioBone Cancellous Cubes | 10 x 20 MM | 20 MM |
NT0043FD | NovioBone Cancellous Cubes | 20 x 20 MM | 30 MM |
NT2108FD | Amnion* Disc – S, Freeze Dried | 8 MM | 0.1 MM |
NT2110FD | Amnion* – M, Freeze Dried | 10 x 10 MM | 0.1 MM |
NT2010FD | Amnion* Disc – M, Freeze Dried | 10 MM | 0.1 MM |
NT2012FD | Amnion* Disc – L, Freeze Dried | 12 MM | 0.1 MM |
NT2120FD | Amnion* – L, Freeze Dried | 20 x 20 MM | 0.1 MM |
NT2016FD | Amnion* – XL, Freeze Dried | 16 MM | 0.1 MM |
NT2060FD | Amnion* – XL, Freeze Dried | 20 x 30 MM | 0.1 MM |
NT1010FD | Dermis – M, Freeze Dried | 10 MM | 0.2 MM |
NT1016FD | Dermis – L, Freeze Dried | 16 MM | 0.2 MM |
NT1030FD | Dermis – XL, Freeze Dried | 25 x 30 MM | 0.2 MM |
* Medtronic EpiDisc and EpiFilm Replacement | |||